Assessment of Serum Magnesium and sex-based differences in magnesium homeostasis’s as the health and Quality of Life at among age groups Libyan population in Misurata, Libya 2025.

Abstract

Context and Goal: Magnesium is vital for maintaining according to the WHO's "intrinsic capacity".  Its levels are positively correlated with the assessment of personal health and quality of life, where the people with average and above-average supply of magnesium become clear have healthy better, compared to people with below-average magnesium status. So, the higher the magnesium levels, the better the quality of life and the health status, in conversely status. This study was aimed to assessment serum magnesium levels, and analyze sex-based differences in magnesium homeostasis, to assess the effectiveness of magnesium (Mg) and its correlation with quality of life. Material and methods’: Cross-sectional study was conducted simultaneously in Qasr Ahmed Hospital - Misurata, the samples were collected from the adult Libyan population residing in Misurata city of Libya. to conduct the test, 617 A total of 617 individuals, comprised of 218 (35.33%) males and 399 (64.67%) females. Were 18 years of age or older, also  the participants of young adult group, 14>17 years old (adolescents).  Findings: The results manifest of (31.12 %) were marked Hypomagnesaemia level compared to (68.88 %) were have normal magnesium level. A comparison of the number of females with hypomagnesaemia was of  (76.04 %) than (23.96 %) at males. Obvious increase rates of  hypomagnesaemia at females with 14.06% in a range of (18-24) old, comparative in males by 5.21% in the same  range of age. Also, an increase in magnesium deficiency rates with age at females, where the percentage reached 13.54% in age range > 65 old. Whereas, the prevalence deficiency levels of hypomagnesaemia of remaining constant between most age groups among males (25-34), (55-64) and (> 65 old) with 3.65 %. In conclusion: Recognizing sex-specific differences in magnesium metabolism is crucial for personalized nutrition and medical care because hormonal variations, life stages, and physiological differences between sexes lead to unique magnesium needs and impacts on health. Which emphasizes the importance of integrating biological gender in dietary recommendations.